One reason thought to be behind the ending was because the show's creator Howard Overman was focusing on a new project. This was the BBC series Atlantis, which ran for two seasons from 2013 to 2015. Another of the reasons the show might have come to an end is because the majority of its original cast had left.

Nathan had switched up his power for a new one which allowed him to perform magic tricks for real. The pair had become new parents with Nathan helping to raise Marnie's infant after the pair fell in love. Speaking about leaving Misfits, Sheehan said his decision came well before season two had finished production.

After bagging a BAFTA for her breakout role as "chavvy" (her words, not ours) Kelly, Socha was found guilty of aggravated assault. By mutual decision, the actress did not return for the show's fourth series.

Kelly becomes bald as Jodi has the power to project temporary alopecia when she becomes angry. ... Kelly takes drugs which invert her power so she begins broadcasting her thoughts, in particular feelings for Nathan telling him she is scared he will hurt her and she thinks she may love him.